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dr5 analyte  (R&D Systems)


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    Structured Review

    R&D Systems dr5 analyte
    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to <t>DR5</t> (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
    Dr5 Analyte, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 42 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+recombinant+trail+r2+fc+chimera+protein/Recombinant+Human+TRAIL+R2%2FTNFRSF10B+Fc+Chimera+Protein%2C+CF/pmc11405282-194-1-3
    Average 93 stars, based on 42 article reviews
    dr5 analyte - by Bioz Stars, 2026-09
    93/100 stars

    Images

    1) Product Images from "A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns"

    Article Title: A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns

    Journal: Nature Nanotechnology

    doi: 10.1038/s41565-024-01676-4

    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
    Figure Legend Snippet: a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.

    Techniques Used: Flow Cytometry

    Related Articles

    Recombinant:

    Article Title: Targeting Death Receptor TRAIL-R2 by Chalcones for TRAIL-Induced Apoptosis in Cancer Cells
    Article Snippet: Soluble recombinant human TRAIL (rhsTRAIL) was purchased from PeproTech Inc. (Rocky Hill, NJ, USA). .. Human recombinant TRAIL-R2/Fc chimera protein was obtained from R & D Systems (Minneapolis, MN, USA). .. The four chalcones: chalcone ( trans -benzylideneacetophenone) ( CH ), isobavachalcone (2′,4′,4-trihydroxy-3′-[3′-methylbut-3′-ethyl]chalcone) ( IC ), licochalcone-A (E-3-[5-(1,1-diethyl-2-propenyl) -4-hydroxy-2-methoxyphenyl]-1-(4-hydroxypenyl)-2-propen-1-one) ( LC ) and xanthohumol (2′,4,4′-tri-hydroxy-3′-prenyl-6′-methoxychalcone) ( XH ) were obtained from Alexis Biochemicals (Lausanne, Switzerland).

    Article Title: Targeting death receptor TRAIL-R2 by chalcones for TRAIL-induced apoptosis in cancer cells.
    Article Snippet: Soluble recombinant human TRAIL (rhsTRAIL) was purchased from PeproTech Inc. (Rocky Hill, NJ, USA). .. Human recombinant TRAIL-R2/Fc chimera protein was obtained from R & D Systems (Minneapolis, MN, USA). .. The four chalcones: chalcone (trans-benzylideneacetophenone) (CH), isobavachalcone (2',4',4-trihydroxy-3'-[3'-methylbut-3'-ethyl]chalcone) (IC), licochalcone-A (E-3-[5-(1,1-diethyl-2-propenyl) -4-hydroxy-2-methoxyphenyl]-1-(4-hydroxypenyl)-2-propen-1-one) (LC) and xanthohumol (2',4,4'-tri-hydroxy-3'-prenyl-6'-methoxychalcone) (XH) were obtained from Alexis Biochemicals (Lausanne, Switzerland).



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    Image Search Results


    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.

    Journal: Nature Nanotechnology

    Article Title: A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns

    doi: 10.1038/s41565-024-01676-4

    Figure Lengend Snippet: a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.

    Article Snippet: The DR5 analyte (R&D Systems, 10140-T2) was diluted from 1,032 nM to 64.5 nM and injected as a single-cycle kinetics experiment, with a flow rate of 30 μl min −1 , and 500 s contact time for each concentration.

    Techniques: Flow Cytometry